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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2005 1
2011 1
2012 2
2013 3
2016 1
2017 2
2018 2
2019 7
2020 3
2021 4
2022 7
2023 2
2024 1

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34 results

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Page 1
Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review).
Katoh M. Katoh M. Int J Mol Med. 2018 Aug;42(2):713-725. doi: 10.3892/ijmm.2018.3689. Epub 2018 May 17. Int J Mol Med. 2018. PMID: 29786110 Free PMC article. Review.
beta-catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion molecules (E-cadherin/CDH1, N-cadherin/CDH2, VE-cadherin/CDH5 and alpha-catenins), transmembrane-type mucins (MUC1/CD227 and MUC16/CA125), signaling regulators (APC, AXIN1, AXIN2 and NHER …
beta-catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion molecules (E-cadherin/CDH1, N-cadherin/CDH2, VE-cadher …
RNA m(6)A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/beta-catenin signaling.
Li Y, Sheng H, Ma F, Wu Q, Huang J, Chen Q, Sheng L, Zhu X, Zhu X, Xu M. Li Y, et al. Cell Death Dis. 2021 May 13;12(5):479. doi: 10.1038/s41419-021-03763-z. Cell Death Dis. 2021. PMID: 33980824 Free PMC article.
Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related deaths worldwide. ...Knockout of AXIN1 sufficiently rescued the inhibitory effect of YTHDF2 depletion on lung cancer cell proliferation, colony-formation, and migration. ...
Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related deaths worldwide. ...Knockout of AXIN1 sufficiently rescu …
WNT/beta-catenin pathway activation via Wnt1 overexpression and Axin1 downregulation correlates with cadherin-catenin complex disruption and increased lymph node involvement in micropapillary-predominant lung adenocarcinoma.
Zhu L, Yang S, Zheng L, Zhang G, Cheng G. Zhu L, et al. J Thorac Dis. 2020 Oct;12(10):5906-5915. doi: 10.21037/jtd-20-1495. J Thorac Dis. 2020. PMID: 33209423 Free PMC article.
BACKGROUND: Micropapillary-predominant adenocarcinoma (MPA) of the lung is associated with extensive lymph node involvement and rapid terminal metastasis. ...METHODS: The present study utilized immunohistochemical staining of surgically resected tissue blocks of MPA and le …
BACKGROUND: Micropapillary-predominant adenocarcinoma (MPA) of the lung is associated with extensive lymph node involvement and rapid …
The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/beta-catentin signaling.
Shen DJ, Jiang YH, Li JQ, Xu LW, Tao KY. Shen DJ, et al. Surg Oncol. 2020 Sep;34:31-39. doi: 10.1016/j.suronc.2020.02.011. Epub 2020 Feb 28. Surg Oncol. 2020. PMID: 32891348
At a molecular level, we determined that RBM47 was able to bind the AXIN1 mRNA, stabilizing it and thereby enhancing the consequent suppression of Wnt/beta-catentin signaling. CONCLUSION: Together our findings reveal that RBM47 targets AXIN1 in order to disrupt Wnt/ …
At a molecular level, we determined that RBM47 was able to bind the AXIN1 mRNA, stabilizing it and thereby enhancing the consequent s …
Targeting TRIM54/Axin1/beta-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma.
Zhu J, Wu Y, Lao S, Shen J, Yu Y, Fang C, Zhang N, Li Y, Zhang R. Zhu J, et al. Front Oncol. 2021 Dec 9;11:759842. doi: 10.3389/fonc.2021.759842. eCollection 2021. Front Oncol. 2021. PMID: 34956880 Free PMC article.
Mechanically, we demonstrated that TRIM54 directly interacts with Axis inhibition proteins 1 (Axin1) and induces E3 ligase-dependent proteasomal turnover of Axin1 and substantially induces sustained activation of wnt/beta-catenin in HCC cell lines. ...Our data sugge …
Mechanically, we demonstrated that TRIM54 directly interacts with Axis inhibition proteins 1 (Axin1) and induces E3 ligase-dependent …
Association between AXIN1 Gene Polymorphisms and Bladder Cancer in Chinese Han Population.
Li Q, Zhang P, Wang Y, Zhang Y, Li K, Song Y, Su M, Zhou B, Zhang L. Li Q, et al. Dis Markers. 2019 Apr 15;2019:3949343. doi: 10.1155/2019/3949343. eCollection 2019. Dis Markers. 2019. PMID: 31143301 Free PMC article.
BACKGROUND: Previous evidence has indicated that the reduction of axis inhibition protein 1 (AXIN1) expression is related with the poor differentiation of non-small-cell lung cancer (NSCLC). However, the potential association between AXIN1 and bladder cancer …
BACKGROUND: Previous evidence has indicated that the reduction of axis inhibition protein 1 (AXIN1) expression is related with the po …
Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney.
Ishiguro H, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y. Ishiguro H, et al. Oncogene. 2001 Aug 16;20(36):5062-6. doi: 10.1038/sj.onc.1204603. Oncogene. 2001. PMID: 11526492
To investigate the detailed biological function of Axin, we searched on a cDNA microarray for genes whose expression was altered by transfer of wild-type AXIN1 into colon-cancer cell line LoVo. Among the genes showing altered expression, we focused on one, termed AXUD1 ( …
To investigate the detailed biological function of Axin, we searched on a cDNA microarray for genes whose expression was altered by transfer …
Wnt signaling pathway-derived score for predicting therapeutic resistance and tumor microenvironment in lung adenocarcinoma.
Zhou HM, Zhao LM. Zhou HM, et al. Front Pharmacol. 2023 Jan 10;13:1091018. doi: 10.3389/fphar.2022.1091018. eCollection 2022. Front Pharmacol. 2023. PMID: 36703749 Free PMC article.
Background: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. ...Conclusion: A innovative 18 genes predictive feature based on transcriptome pattern was found in patients with lung adenocarcinoma. These investigations further promote the i …
Background: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. ...Conclusion: A innovative 18 genes predict …
Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer.
Yang LH, Xu HT, Li QC, Jiang GY, Zhang XP, Zhao HY, Xu K, Wang EH. Yang LH, et al. Tumour Biol. 2013 Apr;34(2):749-57. doi: 10.1007/s13277-012-0604-z. Epub 2012 Nov 29. Tumour Biol. 2013. PMID: 23192643

The results showed that hypermethylated Axin gene promoter and reduced mRNA expression level of Axin could be detected in lung cancer tissues but not in their paired autologous normal lung tissues (P < 0.01). ...Our data indicate that hypermethylated Axin gene si

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The results showed that hypermethylated Axin gene promoter and reduced mRNA expression level of Axin could be detected in lung cancer …
Axin1: A novel scaffold protein joins the antiviral network of interferon.
Guo Y, Bamunuarachchi G, Vaddadi K, Zhu Z, Gandikota C, Ahmed K, Pushparaj S, More S, Xiao X, Yang X, Liang Y, Mukherjee S, Baviskar P, Huang C, Li S, Oomens AGP, Metcalf JP, Liu L. Guo Y, et al. Mol Microbiol. 2022 Dec;118(6):731-743. doi: 10.1111/mmi.14995. Epub 2022 Nov 5. Mol Microbiol. 2022. PMID: 36308071 Free PMC article.
We also found that overexpression of Axin1 and the chemical stabilizer of Axin1, XAV939, reduced influenza virus replication in lung epithelial cells. ...Thus, our studies provide new mechanistic insights into the regulation of the type I IFN response and pre …
We also found that overexpression of Axin1 and the chemical stabilizer of Axin1, XAV939, reduced influenza virus replication i …
34 results